Publications
2024
Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K. Pitfalls in lipid mass spectrometry of mammalian samples — a brief guide for biologists. Nature Reviews Molecular Cell Biology. 2024 Oct;25(10):759-760. Epub 2024. doi: 10.1038/s41580-024-00758-4
Kopczynski D, Ejsing CS, McDonald JG, Bamba T, Baker ES, Bertrand-Michel J et al. The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data. Journal of Lipid Research. 2024 Sept;65(9):100621. doi: 10.1016/j.jlr.2024.100621
Rubenzucker S, Manke MC, Lehmann R, Assinger A, Borst O, Ahrends R. A Targeted, Bioinert LC-MS/MS Method for Sensitive, Comprehensive Analysis of Signaling Lipids. Analytical Chemistry. 2024 Jun 11;96(23):9643-9652. Epub 2024. doi: 10.1021/acs.analchem.4c01388
Kumar M, Has C, Lam-Kamath K, Ayciriex S, Dewett D, Bashir M et al. Eye proteome of Drosophila melanogaster. Proteomics. 2024 May;24(10):2300330. doi: 10.1002/pmic.202300330
Kumar M, Has C, Lam-Kamath K, Ayciriex S, Dewett D, Bashir M et al. Lipidome Unsaturation Affects the Morphology and Proteome of the Drosophila Eye. Journal of Proteome Research. 2024 Apr 5;23(4):1188-1199. Epub 2024 Mar 14. doi: 10.1021/acs.jproteome.3c00570
Witting M, Malik A, Leach A, Bridge A, Aimo L, Conroy MJ et al. Challenges and perspectives for naming lipids in the context of lipidomics. Metabolomics. 2024 Feb;20(1):15. doi: 10.1007/s11306-023-02075-x
2023
Heimerl S, Höring M, Kopczynski D, Sigruener A, Hart C, Burkhardt R et al. Quantification of bulk lipid species in human platelets and their thrombin-induced release. Scientific Reports. 2023 Dec;13(1):6154. doi: 10.1038/s41598-023-33076-4
Kopczynski D, Hoffmann N, Troppmair N, Coman C, Ekroos K, Kreutz MR et al. LipidSpace: Simple Exploration, Reanalysis, and Quality Control of Large-Scale Lipidomics Studies. Analytical Chemistry. 2023 Oct 4;95(41):15236-15244. doi: 10.1021/acs.analchem.3c02449
Troppmair N, Kopczynski D, Assinger A, Lehmann R, Coman C, Ahrends R. Accurate Sphingolipid Quantification Reducing Fragmentation Bias by Nonlinear Models. Analytical Chemistry. 2023 Oct;95(41):15227-15235. doi: 10.1021/acs.analchem.3c02445
de Jonckheere B, Kollotzek F, Münzer P, Göb V, Fischer M, Mott K et al. Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation. Nature Cardiovascular Research. 2023 Sept;2(9):835-852. doi: 10.1038/s44161-023-00325-8
Vondrackova M, Kopczynski D, Hoffmann N, Kuda O. LORA, Lipid Over-Representation Analysis Based on Structural Information. Analytical Chemistry. 2023 Aug 29;95(34):12600-12604. doi: 10.1021/acs.analchem.3c02039
Foest D, Knodel A, Ahrends R, Coman C, Franzke J, Brandt S. Flexible Microtube Plasma for the Consecutive-Ionization of Cholesterol in Nano-Electrospray Mass Spectrometry. Analytical Chemistry. 2023 Jun 6;95(22):8423-8432. doi: 10.1021/acs.analchem.2c04052
Wang Q, Hoene M, Hu C, Fritsche L, Ahrends R, Liebisch G et al. Ex vivo instability of lipids in whole blood: preanalytical recommendations for clinical lipidomics studies. Journal of Lipid Research. 2023 Jun;64(6):100378. doi: 10.1016/j.jlr.2023.100378
Cheung HYF, Zou J, Tantiwong C, Fernandez DI, Huang J, Ahrends R et al. High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors. Cell Calcium. 2023 Jun;112:102738. doi: 10.1016/j.ceca.2023.102738
Chen S, Liang C, Li H, Yu W, Prothiwa M, Kopczynski D et al. Pepstatin-Based Probes for Photoaffinity Labeling of Aspartic Proteases and Application to Target Identification. ACS Chemical Biology. 2023 Apr 21;18(4):686-692. doi: 10.1021/acschembio.2c00946
Schmid R, Heuckeroth S, Korf A, Smirnov A, Myers O, Dyrlund TS et al. Integrative analysis of multimodal mass spectrometry data in MZmine 3. Nature Biotechnology. 2023 Apr;41(4):447-449. doi: 10.1038/s41587-023-01690-2
Ni Z, Wolk M, Jukes G, Espinosa KM, Ahrends R, Aimo L et al. Guiding the choice of informatics software and tools for lipidomics research applications. Nature Methods. 2023 Feb;20(2):193-204. doi: 10.1038/s41592-022-01710-0
Kopczynski D, Krause D, Al Machot F, Schwudke D, Hoffmann N, Ahrends R. The Past and Future of Lipidomics Bioinformatics. In Mass Spectrometry for Lipidomics: Methods and Applications. Wiley. 2023. p. 271-290 doi: 10.1002/9783527836512.ch10
2022
Hohenwallner K, Troppmair N, Panzenboeck L, Kasper C, El Abiead Y, Koellensperger G et al. Decoding Distinct Ganglioside Patterns of Native and Differentiated Mesenchymal Stem Cells by a Novel Glycolipidomics Profiling Strategy. JACS Au. 2022 Nov 28;2(11):2466-2480. doi: 10.1021/jacsau.2c00230
Manke MC, Ahrends R, Borst O. Platelet lipid metabolism in vascular thrombo-inflammation. Clinical Pharmacology and Therapeutics. 2022 Sept;237:108258. doi: 10.1016/j.pharmthera.2022.108258